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MSH6 抗体

MSH6 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2C12F3 unconjugated
产品编号 ABIN7160272
发货至: 中国
  • 抗原 See all MSH6 抗体
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MSH6 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Protein G purified
    免疫原
    Recombinant Human MSH6 Protein
    克隆位点
    2C12F3
    亚型
    IgG
    Top Product
    Discover our top product MSH6 Primary Antibody
  • 应用备注
    Recommended dilution:IHC:1:50-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    别名
    MSH6 (MSH6 产品)
    别名
    GTBP antibody, GTMBP antibody, HNPCC5 antibody, HSAP antibody, p160 antibody, cb326 antibody, wu:fb36c12 antibody, LOC100227810 antibody, AU044881 antibody, AW550279 antibody, Gtmbp antibody, mutS homolog 6 antibody, mutS homolog 6 (E. coli) antibody, DNA mismatch repair protein antibody, MSH6 antibody, msh6 antibody, Msh6 antibody
    背景

    Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa,called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have beendescribed.

    Aliases: MutS Homolog 6,GTBP,HSAP2,DNA Mismatch Repair Protein Msh6,G/T Mismatch-Binding Protein

    UniProt
    P52701
    途径
    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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