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MSH6 抗体

This anti-MSH6 antibody is a 小鼠 单克隆 antibody detecting MSH6 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7160272
发货至: 中国

Quick Overview for MSH6 抗体 (ABIN7160272)

抗原

See all MSH6 抗体
MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

适用

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宿主

  • 77
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小鼠

克隆类型

  • 93
  • 47
  • 1
单克隆

标记

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This MSH6 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA

克隆位点

2C12F3
  • 交叉反应

    纯化方法

    Protein G purified

    免疫原

    Recombinant Human MSH6 Protein

    亚型

    IgG
  • 应用备注

    Recommended dilution:IHC:1:50-1:500,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

    别名

    MSH6

    背景

    Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa,called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have beendescribed.

    Aliases: MutS Homolog 6,GTBP,HSAP2,DNA Mismatch Repair Protein Msh6,G/T Mismatch-Binding Protein

    UniProt

    P52701

    途径

    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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