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MOBKL1A 抗体 (AA 2-216) (Biotin)

This anti-MOBKL1A antibody is a 兔 多克隆 antibody detecting MOBKL1A in ELISA. Suitable for 人.
产品编号 ABIN7160121
发货至: 中国

Quick Overview for MOBKL1A 抗体 (AA 2-216) (Biotin) (ABIN7160121)

抗原

See all MOBKL1A (MOB1B) 抗体
MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

适用

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宿主

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克隆类型

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多克隆

标记

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This MOBKL1A antibody is conjugated to Biotin

应用范围

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ELISA
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    AA 2-216

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human MOB kinase activator 1B protein (2-216AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

    别名

    MOB1B

    背景

    Background: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.

    Aliases: MATS 2 antibody, MATS2 antibody, MGC33910 antibody, Mob 1A antibody, Mob 1B antibody, MOB 4A antibody, MOB kinase activator 1B antibody, Mob1 homolog 1A antibody, MOB1 Mps One Binder homolog B antibody, MOB1 Mps one binder kinase activator like 1A antibody, Mob1A antibody, Mob1B antibody, MOBKL 1A antibody, MOBKL1A antibody, MOL1A_HUMAN antibody, Mps one binder kinase activator like 1A antibody, Mps one binder kinase activator-like 1A antibody, Protein Mob4A antibody

    UniProt

    Q7L9L4
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