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MOBKL1A 抗体

MOB1B 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7245845
发货至: 中国
  • 抗原 See all MOBKL1A (MOB1B) 抗体
    MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
    适用
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    人, 小鼠
    宿主
    • 37
    • 3
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 19
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    This MOBKL1A antibody is un-conjugated
    应用范围
    • 24
    • 21
    • 20
    • 5
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    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Full length fusion protein
    亚型
    IgG
    Top Product
    Discover our top product MOB1B Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.8 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
    别名
    MOB1B (MOB1B 产品)
    别名
    MATS2 antibody, MOB4A antibody, MOBKL1A antibody, 1110003E08Rik antibody, AU015450 antibody, B230364F10 antibody, Mobkl1a antibody, mobkl1a antibody, mobkl1aa antibody, wu:fj65h03 antibody, zgc:56156 antibody, zgc:77872 antibody, MOB1B antibody, mob4a antibody, mats2 antibody, C2orf6 antibody, MOB1 antibody, MOBK1B antibody, Mob4B antibody, cb512 antibody, mobkl1ab antibody, sb:cb512 antibody, zgc:111840 antibody, MOB kinase activator 1B antibody, MOB kinase activator 1Ba antibody, Mps one binder kinase activator-like 1A antibody, mps one binder kinase activator-like 1A antibody, MOB kinase activator 1B L homeolog antibody, MOB kinase activator 1Bb antibody, MOB1B antibody, Mob1b antibody, mob1ba antibody, mol1a antibody, LOC100282811 antibody, LOC100285953 antibody, mob1b antibody, mob1b.L antibody, mob1bb antibody
    背景
    The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene.Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 25 kDa

    UniProt
    Q7L9L4
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