MAP3K11 抗体 (AA 536-693)
Quick Overview for MAP3K11 抗体 (AA 536-693) (ABIN7160017)
抗原
See all MAP3K11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 536-693
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Mitogen-activated protein kinase kinase kinase 11 protein (536-693AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
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别名
- MAP3K11
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背景
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Background: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
Aliases: 2610017K16Rik antibody, EC 2.7.11.25 antibody, M3K11_HUMAN antibody, Map3k11 antibody, MEKK11 antibody, MGC17114 antibody, Mitogen-activated protein kinase kinase kinase 11 antibody, Mixed lineage kinase 3 antibody, Mixed lineage protein kinase 3 antibody, Mlk-3 antibody, Mlk3 antibody, Protein tyrosine kinase PTK1 antibody, PTK1 antibody, RHOE antibody, SH3 domain containing proline rich kinase antibody, SPRK antibody, Src-homology 3 domain-containing proline-rich kinase antibody
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UniProt
- Q16584
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途径
- MAPK Pathway, Interferon-gamma Pathway
抗原
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