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MFN2 抗体 (AA 61-158)

This anti-MFN2 antibody is a 兔 多克隆 antibody detecting MFN2 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7159968
发货至: 中国

Quick Overview for MFN2 抗体 (AA 61-158) (ABIN7159968)

抗原

See all MFN2 抗体
MFN2 (Mitofusin 2 (MFN2))

适用

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宿主

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克隆类型

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多克隆

标记

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This MFN2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    AA 61-158

    交叉反应

    人, 大鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Mitofusin-2 protein (61-158AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:200-1:3000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MFN2 (Mitofusin 2 (MFN2))

    别名

    MFN2

    背景

    Background: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.

    Aliases: CMT2A antibody, CMT2A2 antibody, CPRP 1 antibody, CPRP1 antibody, EC 3.6.5.- antibody, Fzo antibody, HSG antibody, hyperplasia suppressor gene antibody, Hypertension related protein 1 antibody, KIAA0214 antibody, MARF antibody, MFN 2 antibody, Mfn2 antibody, MFN2_HUMAN antibody, Mitochondrial assembly regulatory factor antibody, Mitofusin-2 antibody, Mitofusin2 antibody, Transmembrane GTPase MFN2 antibody

    UniProt

    O95140

    途径

    Skeletal Muscle Fiber Development
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