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Menin 抗体 (AA 1-615)

This anti-Menin antibody is a 兔 多克隆 antibody detecting Menin in ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7159407
发货至: 中国

Quick Overview for Menin 抗体 (AA 1-615) (ABIN7159407)

抗原

See all Menin (MEN1) 抗体
Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Menin antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-615

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Menin protein (1-615AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

    别名

    MEN1

    背景

    Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates \\\'Lys-4\\\' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

    Aliases: MEA 1 antibody, MEA1 antibody, MEN 1 antibody, Men1 antibody, MEN1_HUMAN antibody, Menin antibody, Multiple Endocrine Adenomatosis 1 antibody, Multiple Endocrine Neoplasia 1 antibody, SCG 2 antibody, SCG2 antibody, Suppressor Candidate Gene 2 antibody, Wermer syndrome antibody, ZES antibody, Zollinger Ellison Syndrome antibody

    UniProt

    O00255

    途径

    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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