Menin 抗体 (AA 1-615)
Quick Overview for Menin 抗体 (AA 1-615) (ABIN7159407)
抗原
See all Menin (MEN1) 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 1-615
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                                            交叉反应
- 人
- 
                                            纯化方法
- >95%, Protein G purified
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                                            免疫原
- Recombinant Human Menin protein (1-615AA)
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                                            亚型
- IgG
 
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                                            应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
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                        Preservative: 0.03 % Proclin 300
 Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
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                                            别名
- MEN1
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                                            背景
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                        Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates \\\'Lys-4\\\' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair. Aliases: MEA 1 antibody, MEA1 antibody, MEN 1 antibody, Men1 antibody, MEN1_HUMAN antibody, Menin antibody, Multiple Endocrine Adenomatosis 1 antibody, Multiple Endocrine Neoplasia 1 antibody, SCG 2 antibody, SCG2 antibody, Suppressor Candidate Gene 2 antibody, Wermer syndrome antibody, ZES antibody, Zollinger Ellison Syndrome antibody 
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                                            UniProt
- O00255
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                                            途径
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
 抗原
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