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CD46 抗体 (AA 164-325) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-CD46 antibody (ABIN7159321) specifically detects CD46 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7159321
发货至: 中国
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Quick Overview for CD46 抗体 (AA 164-325) (Biotin) (ABIN7159321)

抗原

See all CD46 抗体
CD46

适用

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宿主

  • 90
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克隆类型

  • 94
  • 68
多克隆

标记

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This CD46 antibody is conjugated to Biotin

应用范围

  • 94
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  • 9
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ELISA
  • 抗原表位

    • 16
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    AA 164-325

    原理

    CD46 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Membrane cofactor protein (164-325AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CD46

    别名

    CD46

    背景

    Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

    Aliases: AHUS2 antibody, Antigen defined by monoclonal antibody TRA 2 10 antibody, Antigen identified by monoclonal antibody TRA 2 10 antibody, CD46 antibody, CD46 antigen antibody, CD46 antigen complement regulatory protein antibody, CD46 Molecule antibody, CD46 Molecule complement regulatory protein antibody, Complement membrane cofactor protein antibody, MCP antibody, MCP_HUMAN antibody, Measles virus receptor antibody, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) antibody, Membrane cofactor protein antibody, MGC26544 antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Trophoblast leucocyte common antigen antibody, Trophoblast leukocyte common antigen antibody, Trophoblast lymphocyte cross reactive antigen antibody

    UniProt

    P15529

    途径

    Regulation of Actin Filament Polymerization
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