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MASP1 抗体 (AA 20-699) (HRP)

This anti-MASP1 antibody is a 兔 多克隆 antibody detecting MASP1 in ELISA. Suitable for 人.
产品编号 ABIN7158973
发货至: 中国

Quick Overview for MASP1 抗体 (AA 20-699) (HRP) (ABIN7158973)

抗原

See all MASP1 抗体
MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))

适用

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宿主

  • 50
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克隆类型

  • 52
  • 5
多克隆

标记

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This MASP1 antibody is conjugated to HRP

应用范围

  • 48
  • 19
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  • 5
  • 3
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  • 1
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ELISA
  • 抗原表位

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    AA 20-699

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Mannan-binding lectin serine protease 1 protein (20-699AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))

    别名

    MASP1

    背景

    Background: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.

    Aliases: MASP1 antibody, CRARF antibody, CRARF1 antibody, PRSS5Mannan-binding lectin serine protease 1 antibody, EC 3.4.21.- antibody, Complement factor MASP-3 antibody, Complement-activating component of Ra-reactive factor antibody, Mannose-binding lectin-associated serine protease 1 antibody, MASP-1 antibody, Mannose-binding protein-associated serine protease antibody, Ra-reactive factor serine protease p100 antibody, RaRF antibody, Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain] antibody

    UniProt

    P48740

    途径

    Complement System
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