KDM5A 抗体 (AA 437-603)
Quick Overview for KDM5A 抗体 (AA 437-603) (ABIN7158708)
抗原
See all KDM5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 437-603
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Lysine-specific demethylase 5A protein (437-603AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
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别名
- KDM5A
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背景
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Background: Histone demethylase that specifically demethylates \'Lys-4\' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \'Lys-9\', H3 \'Lys-27\', H3 \'Lys-36\', H3 \'Lys-79\' or H4 \'Lys-20\'. Demethylates trimethylated and dimethylated but not monomethylated H3 \'Lys-4\'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12.
Aliases: Histone demethylase JARID1A antibody, JARID1A antibody, Jumonji/ARID domain containing protein 1A antibody, Jumonji/ARID domain-containing protein 1A antibody, Kdm5a antibody, KDM5A_HUMAN antibody, Lysine-specific demethylase 5A antibody, RBBP-2 antibody, RBBP2 antibody, RBP2 antibody, Retinoblastoma binding protein 2 antibody, Retinoblastoma-binding protein 2 antibody
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UniProt
- P29375
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途径
- Chromatin Binding, Warburg Effect
抗原
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