KDM4A 抗体 (AA 127-364)
Quick Overview for KDM4A 抗体 (AA 127-364) (ABIN7158695)
抗原
See all KDM4A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 127-364
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Lysine-specific demethylase 4A protein (127-364AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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别名
- KDM4A
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背景
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Background: Histone demethylase that specifically demethylates \'Lys-9\' and \'Lys-36\' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \'Lys-4\', H3 \'Lys-27\' nor H4 \'Lys-20\'. Demethylates trimethylated H3 \'Lys-9\' and H3 \'Lys-36\' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Aliases: JHDM3A antibody, JmjC domain containing histone demethylation protein 3A antibody, JmjC domain-containing histone demethylation protein 3A antibody, JMJD2 antibody, JMJD2A antibody, jumonji C domain containing histone demethylase 3A antibody, Jumonji domain containing 2 antibody, Jumonji domain containing 2A antibody, Jumonji domain containing protein 2A antibody, Jumonji domain-containing protein 2A antibody, KDM4A antibody, KDM4A_HUMAN antibody, KIAA0677 antibody, Lysine (K) specific demethylase 4A antibody, Lysine-specific demethylase 4A antibody, TDRD14A antibody, Tudor domain containing 14A antibody
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UniProt
- O75164
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途径
- Warburg Effect
抗原
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