KIT Ligand 抗体 (AA 26-214)
Quick Overview for KIT Ligand 抗体 (AA 26-214) (ABIN7157685)
抗原
See all KIT Ligand (KITLG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-214
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Kit ligand protein (26-214AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:2000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KIT Ligand (KITLG)
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别名
- KITLG
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背景
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Background: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.
Aliases: C kit ligand antibody, C-kit ligand antibody, Ckit ligand antibody, DCUA antibody, DFNA69 antibody, DKFZp686F2250 antibody, familial progressive hyperpigmentation 2 antibody, FPH2 antibody, FPHH antibody, KIT ligand antibody, Kitl antibody, KITLG antibody, KL 1 antibody, KL1 antibody, Mast cell growth factor antibody, MGF antibody, MGF stem cell factor antibody, SCF antibody, SCF_HUMAN antibody, SF antibody, SHEP7 antibody, sKITLG antibody, Soluble KIT ligand antibody, Steel factor antibody, steel, mouse, homolog of antibody, Stem cell factor antibody, Stem cell factor precursor antibody
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UniProt
- P21583
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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