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KIT Ligand 抗体 (AA 26-214)

This anti-KIT Ligand antibody is a 兔 多克隆 antibody detecting KIT Ligand in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7157685
发货至: 中国

Quick Overview for KIT Ligand 抗体 (AA 26-214) (ABIN7157685)

抗原

See all KIT Ligand (KITLG) 抗体
KIT Ligand (KITLG)

适用

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宿主

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克隆类型

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多克隆

标记

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This KIT Ligand antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    AA 26-214

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Kit ligand protein (26-214AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:2000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KIT Ligand (KITLG)

    别名

    KITLG

    背景

    Background: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

    Aliases: C kit ligand antibody, C-kit ligand antibody, Ckit ligand antibody, DCUA antibody, DFNA69 antibody, DKFZp686F2250 antibody, familial progressive hyperpigmentation 2 antibody, FPH2 antibody, FPHH antibody, KIT ligand antibody, Kitl antibody, KITLG antibody, KL 1 antibody, KL1 antibody, Mast cell growth factor antibody, MGF antibody, MGF stem cell factor antibody, SCF antibody, SCF_HUMAN antibody, SF antibody, SHEP7 antibody, sKITLG antibody, Soluble KIT ligand antibody, Steel factor antibody, steel, mouse, homolog of antibody, Stem cell factor antibody, Stem cell factor precursor antibody

    UniProt

    P21583

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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