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KNG1 抗体 (AA 390-644) (Biotin)

This anti-KNG1 antibody is a Rabbit Polyclonal antibody detecting KNG1 in IHC, ELISA. Suitable for Human.
产品编号 ABIN7157682
发货至: 中国

Quick Overview for KNG1 抗体 (AA 390-644) (Biotin) (ABIN7157682)

抗原

See all KNG1 抗体
KNG1 (Kininogen 1 (KNG1))

适用

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宿主

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克隆类型

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多克隆

标记

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This KNG1 antibody is conjugated to Biotin

应用范围

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Immunohistochemistry (IHC), ELISA
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    AA 390-644

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Kininogen-1 protein (390-644AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KNG1 (Kininogen 1 (KNG1))

    别名

    KNG1

    背景

    Background: Kininogens are inhibitors of thiol proteases, (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII, (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes, (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action), (5) LMW-kininogen inhibits the aggregation of thrombocytes, (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.

    Aliases: Alpha-2-thiol proteinase inhibitor antibody, BDK antibody, BK antibody, Bradykinin antibody, Bradykinin included antibody, Fitzgerald factor antibody, FLAUJEAC FACTOR antibody, High molecular weight kininogen antibody, HMWK antibody, Ile-Ser-Bradykinin antibody, Kallidin I antibody, Kallidin II antibody, KNG antibody, KNG1 antibody, KNG1_HUMAN antibody, Low molecular weight growth-promoting factor antibody, WILLIAMS FACTOR antibody, Williams-Fitzgerald-Flaujeac factor antibody

    UniProt

    P01042

    途径

    ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
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