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NDC8 (AA 1-249) 抗体 (HRP)

适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7157664
发货至: 中国
  • 抗原
    NDC8
    抗原表位
    • 3
    • 1
    AA 1-249
    适用
    宿主
    • 4
    克隆类型
    • 4
    多克隆
    标记
    • 2
    • 1
    • 1
    HRP
    应用范围
    • 3
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Kinetochore protein NDC80 homolog protein (1-249AA)
    亚型
    IgG
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    NDC8
    背景

    Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).

    Aliases: from Entrez Gene , antibody, HEC antibody, Highly expressed in cancer antibody, Highly expressed in cancer protein antibody, Highly expressed in cancer rich in leucine heptad repeats antibody, HsHec1 antibody, hsNDC80 antibody, Kinetochore associated 2 antibody, Kinetochore associated protein 2 antibody, Kinetochore protein Hec1 antibody, Kinetochore protein NDC80 homolog antibody, Kinetochore-associated protein 2 antibody, KNTC2 antibody, ndc80 antibody, NDC80 homolog kinetochore complex component antibody, NDC80 kinetochore complex component homolog antibody, NDC80, S. cerevisiae, homolog of antibody, NDC80_HUMAN antibody, Retinoblastoma associated protein HEC antibody, Retinoblastoma-associated protein HEC antibody, TID3 antibody

    UniProt
    O14777
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