KIF14 抗体 (AA 261-531) (HRP)
Quick Overview for KIF14 抗体 (AA 261-531) (HRP) (ABIN7157598)
抗原
See all KIF14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-531
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Kinesin-like protein KIF14 protein (261-531AA)
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亚型
- IgG
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anti-Kinesin Family Member 14 (KIF14) antibody
KIF14 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 14 (KIF14) (AA 1399-1648) antibodyKIF14 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 14 (KIF14) (AA 261-531) antibodyKIF14 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 14 (KIF14) (N-Term) antibodyKIF14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KIF14 (Kinesin Family Member 14 (KIF14))
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别名
- KIF14
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背景
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Background: Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).
Aliases: KIAA0042 antibody, KIF 14 antibody, KIF14 antibody, KIF14_HUMAN antibody, Kinesin Family Member 14 antibody, Kinesin like protein KIF14 antibody, Kinesin-like protein KIF14 antibody, MGC142302 antibody
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UniProt
- Q15058
抗原
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