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KSR2 抗体 (AA 159-296) (FITC)

This anti-KSR2 antibody is a 兔 多克隆 antibody detecting KSR2 in . Suitable for 人.
产品编号 ABIN7157560
发货至: 中国

Quick Overview for KSR2 抗体 (AA 159-296) (FITC) (ABIN7157560)

抗原

See all KSR2 抗体
KSR2 (Kinase Suppressor of Ras 2 (KSR2))

适用

  • 42
  • 15

宿主

  • 36
  • 6

克隆类型

  • 39
  • 3
多克隆

标记

  • 21
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KSR2 antibody is conjugated to FITC

应用范围

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  • 抗原表位

    • 8
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 159-296

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Kinase suppressor of Ras 2 protein (159-296AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KSR2 (Kinase Suppressor of Ras 2 (KSR2))

    别名

    KSR2

    背景

    Background: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

    Aliases: FLJ25965 antibody, hKSR 2 antibody, hKSR2 antibody, Kinase suppressor of Ras 2 antibody, KSR 2 antibody, Ksr2 antibody, KSR2_HUMAN antibody

    UniProt

    Q6VAB6
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