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KEAP1 抗体 (AA 1-624)

This anti-KEAP1 antibody is a 兔 多克隆 antibody detecting KEAP1 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7157263
发货至: 中国

Quick Overview for KEAP1 抗体 (AA 1-624) (ABIN7157263)

抗原

See all KEAP1 抗体
KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

适用

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宿主

  • 92
  • 10
  • 1

克隆类型

  • 90
  • 13
多克隆

标记

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This KEAP1 antibody is un-conjugated

应用范围

  • 86
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  • 16
  • 13
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  • 9
  • 6
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 15
    • 12
    • 12
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 1-624

    交叉反应

    人, 小鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Kelch-like ECH-associated protein 1 protein (1-624AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

    别名

    KEAP1

    背景

    Background: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

    Aliases: Cytosolic inhibitor of Nrf2 antibody, INrf 2 antibody, INrf2 antibody, Keap 1 antibody, KEAP1 antibody, KEAP1_HUMAN antibody, Kelch like ECH associated protein 1 antibody, Kelch like family member 19 antibody, Kelch like protein 19 antibody, Kelch-like ECH-associated protein 1 antibody, Kelch-like protein 19 antibody, KIAA0132 antibody, KLHL 19 antibody, KLHL19 antibody, MGC10630 antibody, MGC1114 antibody, MGC20887 antibody, MGC4407 antibody, MGC9454 antibody

    UniProt

    Q14145

    途径

    Maintenance of Protein Location
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