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IFITM3 抗体 (AA 1-57) (FITC)

This FITC-conjugated 兔 多克隆 anti-IFITM3 antibody specifically detects IFITM3 in not_set. The antibody is reactive with 人 samples.
产品编号 ABIN7156689
发货至: 中国
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Quick Overview for IFITM3 抗体 (AA 1-57) (FITC) (ABIN7156689)

抗原

See all IFITM3 抗体
IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

适用

  • 41
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1

宿主

  • 33
  • 6
  • 3

克隆类型

  • 34
  • 8
多克隆

标记

  • 31
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IFITM3 antibody is conjugated to FITC

应用范围

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  • 抗原表位

    • 9
    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-57

    原理

    IFITM3 Antibody, FITC conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Interferon-induced transmembrane protein 3 protein (1-57AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

    别名

    IFITM3

    背景

    Background: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.

    Aliases: 1 8U antibody, Fragilis antibody, IFITM3 antibody, IFM3_HUMAN antibody, Interferon induced transmembrane protein 3 (1 8U) antibody, Interferon Induced Transmembrane Protein 3 antibody, Interferon inducible antibody, Interferon inducible protein 1 8U antibody, Interferon Inducible Protein 15 antibody, Interferon Inducible Protein Homolog antibody, Interferon-induced transmembrane protein 3 antibody, Interferon-inducible protein 1-8U antibody, IP15 antibody

    UniProt

    Q01628
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