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Integrin beta 7 抗体 (AA 1-140)

This anti-Integrin beta 7 antibody is a 兔 多克隆 antibody detecting Integrin beta 7 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7156498
发货至: 中国

Quick Overview for Integrin beta 7 抗体 (AA 1-140) (ABIN7156498)

抗原

See all Integrin beta 7 (ITGB7) 抗体
Integrin beta 7 (ITGB7)

适用

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宿主

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克隆类型

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多克隆

标记

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This Integrin beta 7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    AA 1-140

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Integrin beta-7 protein (1-140AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Integrin beta 7 (ITGB7)

    别名

    ITGB7

    背景

    Background: Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.

    Aliases: Gut homing receptor beta subunit antibody, Integrin beta 7 subunit antibody, Integrin beta-7 antibody, Integrin beta-P antibody, Integrin, beta 7 antibody, ITB7 antibody, ITB7_HUMAN antibody, Itgb7 antibody, Ly69 antibody, M290 IEL antigen antibody

    UniProt

    P26010

    途径

    Integrin Complex
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