ING4 抗体 (AA 75-249)
Quick Overview for ING4 抗体 (AA 75-249) (ABIN7156253)
抗原
See all ING4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-249
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Inhibitor of growth protein 4 protein (75-249AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
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别名
- ING4
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背景
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Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor\'s (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).
Aliases: Brain my036 protein antibody, Candidate tumor suppressor p33 ING 1 homolog antibody, Candidate tumor suppressor p33 ING1 homolog antibody, D6Wsu147e antibody, D6Xrf92 antibody, ING 1 like protein antibody, ING 4 antibody, ING1 like protein antibody, ING4 antibody, ING4_HUMAN antibody, Inhibitor of growth family member 4 antibody, Inhibitor of growth family member 4 long isoform antibody, Inhibitor of growth protein 4 antibody, MGC12557 antibody, my036 antibody, p29 ING 4 antibody, p29 ING4 antibody, p29ING4 antibody
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UniProt
- Q9UNL4
抗原
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