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ING4 抗体 (AA 75-249)

This anti-ING4 antibody is a 兔 多克隆 antibody detecting ING4 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7156253
发货至: 中国

Quick Overview for ING4 抗体 (AA 75-249) (ABIN7156253)

抗原

See all ING4 抗体
ING4 (Inhibitor of Growth Family, Member 4 (ING4))

适用

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宿主

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克隆类型

  • 29
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多克隆

标记

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This ING4 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 75-249

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Inhibitor of growth protein 4 protein (75-249AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ING4 (Inhibitor of Growth Family, Member 4 (ING4))

    别名

    ING4

    背景

    Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor\'s (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).

    Aliases: Brain my036 protein antibody, Candidate tumor suppressor p33 ING 1 homolog antibody, Candidate tumor suppressor p33 ING1 homolog antibody, D6Wsu147e antibody, D6Xrf92 antibody, ING 1 like protein antibody, ING 4 antibody, ING1 like protein antibody, ING4 antibody, ING4_HUMAN antibody, Inhibitor of growth family member 4 antibody, Inhibitor of growth family member 4 long isoform antibody, Inhibitor of growth protein 4 antibody, MGC12557 antibody, my036 antibody, p29 ING 4 antibody, p29 ING4 antibody, p29ING4 antibody

    UniProt

    Q9UNL4
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