HORMAD2 抗体 (AA 14-307) (FITC)
Quick Overview for HORMAD2 抗体 (AA 14-307) (FITC) (ABIN7155903)
抗原
See all HORMAD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-307
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human HORMA domain-containing protein 2 protein (14-307AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HORMAD2 (HORMA Domain Containing 2 (HORMAD2))
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别名
- HORMAD2
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背景
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Background: Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation.
Aliases: 4930529M09Rik antibody, CT46.2 antibody, HORM2_HUMAN antibody, HORMA domain containing 2 antibody, HORMA domain-containing protein 2 antibody, Hormad2 antibody, MGC26710 antibody, RP23-329P17.4 antibody
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UniProt
- Q8N7B1
抗原
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