Nanog 抗体 (AA 1-305)
Quick Overview for Nanog 抗体 (AA 1-305) (ABIN7155816)
抗原
See all Nanog (NANOG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-305
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G purified
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免疫原
- Recombinant Human Homeobox protein NANOG protein (1-305AA)
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亚型
- IgG1, IgG1 kappa
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anti-Nanog Homeobox (NANOG) antibody
NANOG 适用: 人 WB, ELISA, IF, IHC, ICC, IHC (p), IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nanog Homeobox (NANOG) (AA 101-200) antibodyNANOG 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nanog Homeobox (NANOG) (AA 71-170) antibodyNANOG 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nanog Homeobox (NANOG) (AA 15-49) antibodyNANOG 适用: 人 WB, ELISA, IF, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Nanog Homeobox (NANOG) (AA 98-195) antibodyNANOG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-Nanog Homeobox (NANOG) (AA 98-195) antibodyNANOG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Nanog Homeobox (NANOG) (Internal Region) antibodyVerified NANOG 适用: 人 WB, ELISA, IF, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Nanog Homeobox (NANOG) (AA 1-100) antibodyNANOG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nanog Homeobox (NANOG) (AA 20-166) antibodyNANOG 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 1E6C4 unconjugated
anti-Nanog Homeobox (NANOG) (AA 267-292) antibodyNANOG 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:2000, ICC:1:50-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Nanog (NANOG) (Nanog Homeobox (NANOG))
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别名
- NANOG
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背景
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Background: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Binds to the POU5F1/OCT4 promoter (PubMed:25825768). Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.
Aliases: Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog), NANOG
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UniProt
- Q9H9S0
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途径
- Stem Cell Maintenance
抗原
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