SETDB1 抗体 (AA 1-397)
Quick Overview for SETDB1 抗体 (AA 1-397) (ABIN7155521)
抗原
See all SETDB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-397
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交叉反应
- 人, 大鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Histone-lysine N-methyltransferase SETDB1 protein (1-397AA)
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亚型
- IgG
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anti-SET Domain, Bifurcated 1 (SETDB1) (AA 2-100) antibody
SETDB1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A3 unconjugated
anti-SET Domain, Bifurcated 1 (SETDB1) antibodySETDB1 适用: 人, 小鼠, 猴 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 5H6A12 unconjugated
anti-SET Domain, Bifurcated 1 (SETDB1) antibodySETDB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5H6D4 unconjugated
anti-SET Domain, Bifurcated 1 (SETDB1) antibodySETDB1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain, Bifurcated 1 (SETDB1) (AA 1-397) antibodySETDB1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain, Bifurcated 1 (SETDB1) (AA 1193-1225) antibodySETDB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SET Domain, Bifurcated 1 (SETDB1) (AA 2-100) antibodySETDB1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SET Domain, Bifurcated 1 (SETDB1) (AA 1193-1225), (C-Term) antibodySETDB1 适用: 人 WB 宿主: 兔 Polyclonal RB5748 unconjugated
anti-SET Domain, Bifurcated 1 (SETDB1) (AA 1050-1075) antibodySETDB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SETDB1 (SET Domain, Bifurcated 1 (SETDB1))
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别名
- SETDB1
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背景
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Background: Histone methyltransferase that specifically trimethylates \\\'Lys-9\\\' of histone H3. H3 \\\'Lys-9\\\' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 \\\'Lys-9\\\' trimethylation is coordinated with DNA methylation. Probably forms a complex with MBD1 and ATF7IP that represses transcription and couples DNA methylation and histone \\\'Lys-9\\\' trimethylation. Its activity is dependent on MBD1 and is heritably maintained through DNA replication by being recruited by CAF-1. SETDB1 is targeted to histone H3 by TRIM28/TIF1B, a factor recruited by KRAB zinc-finger proteins.
Aliases: AU022152 antibody, EC 2.1.1.43 antibody, ERG-associated protein with SET domain antibody, ESET antibody, H3 K9 HMTase 4 antibody, H3-K9-HMTase 4 antibody, H3-K9-HMTase4 antibody, Histone H3 K9 methyltransferase 4 antibody, Histone H3-K9 methyltransferase 4 antibody, Histone-lysine N-methyltransferase SETDB1 antibody, KG1T antibody, KIAA0067 antibody, KMT1E antibody, Lysine N-methyltransferase 1E antibody, MGC90670 antibody, mKIAA0067 antibody, SET domain bifurcated 1 antibody, Set domain protein, bifurcated, 1 antibody, SETB1_HUMAN antibody, Setdb1 antibody
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UniProt
- Q15047
抗原
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