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HINT1 抗体 (AA 2-126)

This anti-HINT1 antibody is a 兔 多克隆 antibody detecting HINT1 in ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7155253
发货至: 中国

Quick Overview for HINT1 抗体 (AA 2-126) (ABIN7155253)

抗原

See all HINT1 抗体
HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HINT1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 2-126

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Histidine triad nucleotide-binding protein 1 protein (2-126AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

    别名

    HINT1

    背景

    Background: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5\\\'monophosphoramidate (AMP-NH2), adenosine 5\\\'monophosphomorpholidate (AMP-morpholidate) and guanosine 5\\\'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5\\\'-O-phosphorothioate and guanosine 5\\\'-O-phosphorothioate to the corresponding nucleoside 5\\\'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

    Aliases: Adenosine 5' monophosphoramidase antibody, Adenosine 5''-monophosphoramidase antibody, HINT 1 antibody, HINT1 antibody, HINT1_HUMAN antibody, Histidine triad nucleotide binding protein 1 antibody, Histidine triad nucleotide-binding protein 1 antibody, PKCI 1 antibody, PKCI-1 antibody, PKCI1 antibody, PRKCNH1 antibody, Protein kinase C inhibitor 1 antibody, Protein kinase C interacting protein 1 antibody, Protein kinase C-interacting protein 1 antibody

    UniProt

    P49773
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