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Hsc70 抗体 (AA 2-646)

This 小鼠 单克隆 anti-Hsc70 antibody (Clone 2G8F6) specifically detects Hsc70 in WB, IHC, ELISA, IP 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7154883
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Hsc70 抗体 (AA 2-646) (ABIN7154883)

抗原

See all Hsc70 (HSPA8) 抗体
Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

适用

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宿主

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小鼠

克隆类型

  • 78
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单克隆

标记

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This Hsc70 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)

克隆位点

2G8F6
  • 抗原表位

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    AA 2-646

    原理

    HSPA8 Monoclonal Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Protein A purified

    纯度

    >95 %

    免疫原

    Recombinant Human Heat shock cognate 71 kDa protein (2-646AA)

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

    别名

    HSPA8

    背景

    Background: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP

    Aliases: Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1), HSPA8, HSC70 HSP73 HSPA10

    UniProt

    P11142
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