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HEY1 抗体 (AA 200-300)

This anti-HEY1 antibody is a 兔 多克隆 antibody detecting HEY1 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7154814
发货至: 中国

Quick Overview for HEY1 抗体 (AA 200-300) (ABIN7154814)

抗原

See all HEY1 抗体
HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HEY1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 200-300

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Hairy/enhancer-of-split related with YRPW motif protein 1 protein (200-300AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:200-1:500,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

    别名

    HEY1

    背景

    Background: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737).

    Aliases: Basic helix loop helix protein OAF1 antibody, bHLHb31 antibody, Cardiovascular helix loop-helix factor 2 antibody, Cardiovascular helix-loop-helix factor 2 antibody, CHF-2 antibody, CHF2 antibody, Class B basic helix-loop-helix protein 31 antibody, Hairy and enhancer of split related protein 1 antibody, Hairy and enhancer of split-related protein 1 antibody, Hairy enhancer-of-split related with YRPW motif protein 1 antibody, Hairy related transcription factor 1 antibody, Hairy-related transcription factor 1 antibody, Hairy/enhancer of split related with YRPW motif 1 antibody, Hairy/enhancer-of-split related with YRPW motif protein 1 antibody, HERP2 antibody, HES related repressor protein 1 antibody, HES-related repressor protein 1 antibody, HES-related repressor protein 2 antibody, HESR-1 antibody, HESR1 antibody, HEY 1 antibody, hey1 antibody, HEY1_HUMAN antibody, hHRT1 antibody, HRT-1 antibody, HRT1 antibody, OAF1 antibody

    UniProt

    Q9Y5J3

    途径

    Tube Formation
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