GREM1 抗体 (AA 18-184) (HRP)
Quick Overview for GREM1 抗体 (AA 18-184) (HRP) (ABIN7154451)
抗原
See all GREM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-184
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Gremlin-1 protein (18-184AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GREM1 (Gremlin 1 (GREM1))
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别名
- GREM1
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背景
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Background: Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2, inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity).
Aliases: BMP antagonist 1 antibody, Cell proliferation inducing gene 2 protein antibody, Cell proliferation-inducing gene 2 protein antibody, CKTSF1B1 antibody, colorectal adenoma and carcinoma 1 antibody, Cysteine knot superfamily 1 antibody, Cysteine knot superfamily 1, BMP antagonist 1 antibody, Cysteine knot superfamily BMP antagonist 1 antibody, DAN domain family member 2 antibody, DAND2 antibody, Down regulated in Mos-transformed cells protein antibody, Down-regulated in Mos-transformed cells protein antibody, DRM antibody, grem1 antibody, GREM1_HUMAN antibody, Gremlin 1 homolog, cysteine knot superfamily antibody, Gremlin 1 like protein antibody, Gremlin 1, cysteine knot superfamily, homolog antibody, GREMLIN antibody, Gremlin-1 antibody, Gremlin1 antibody, IHG-2 antibody, IHG2 antibody, Increased in high glucose 2 antibody, Increased in high glucose protein 2 antibody, PIG2 antibody, Proliferation inducing gene 2 antibody, proliferation inducing gene 2 protein antibody
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UniProt
- O60565
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途径
- Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
抗原
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