GRHL3 抗体 (AA 31-182) (FITC)
Quick Overview for GRHL3 抗体 (AA 31-182) (FITC) (ABIN7154382)
抗原
See all GRHL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-182
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Grainyhead-like protein 3 homolog protein (31-182AA)
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亚型
- IgG
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anti-Grainyhead-Like 3 (GRHL3) (AA 431-480) antibody
GRHL3 适用: 人, 小鼠, 犬, Cow, 豚鼠, 马, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 3 (GRHL3) (AA 101-200) antibodyGRHL3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C5 unconjugated
anti-Grainyhead-Like 3 (GRHL3) (AA 529-578) antibodyGRHL3 适用: 人, 小鼠, 犬, Cow, 豚鼠, 马, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 3 (GRHL3) (C-Term) antibodyGRHL3 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 3 (GRHL3) (C-Term) antibodyGRHL3 适用: 人, 小鼠, 犬, 大鼠, Cow, 豚鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 3 (GRHL3) (C-Term) antibodyGRHL3 适用: 人, 小鼠, 犬, 大鼠, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 3 (GRHL3) (AA 31-182) antibodyGRHL3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 3 (GRHL3) (AA 428-477) antibodyGRHL3 适用: 人, 小鼠, 猴 WB, ChIP 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GRHL3 (Grainyhead-Like 3 (GRHL3))
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别名
- GRHL3
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背景
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Background: Transcription factor playing important roles in primary neurulation and in the differentiation of stratified epithelia of both ectodermal and endodermal origin (By similarity). Binds directly to the consensus DNA sequence 5\'-AACCGGTT-3\' acting as an activator and repressor on distinct target genes (PubMed:21081122, PubMed:25347468). xhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair (By similarity). Exhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair but is essential to form the epidermal barrier with TGM3 as critical direct target gene among others. Despite being dispensable during normal epidermal homeostasis in the adulthood, is again required for barrier repair after immune-mediated epidermal damage, regulates distinct gene batteries in embryonic epidermal differentiation and adult epidermal barrier reformation after injury. Plays unique and cooperative roles with GRHL2 in establishing distinct zones of primary neurulation. Essential for spinal closure, functions cooperatively with GRHL2 in closure 2 (forebrain/midbrain boundary) and posterior neuropore closure (By similarity). Also required for proper development of the oral periderm (PubMed:24360809). No genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity (PubMed:21081122).
Aliases: Drosophila antibody, Grainyhead like 3 antibody, Grainyhead like protein 3 homolog antibody, Grainyhead-like protein 3 homolog antibody, grhl3 antibody, GRHL3_HUMAN antibody, Sister of mammalian grainyhead antibody, Sister of mammalian grainyhead protein antibody, SOM antibody, TFCP2L4 antibody, Transcription factor CP2 like 4 antibody, Transcription factor CP2-like 4 antibody
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UniProt
- Q8TE85
抗原
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