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GRHL3 抗体 (C-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-GRHL3 antibody is suitable to detect GRHL3 in samples from 人, 小鼠, 犬, 大鼠, Cow, 豚鼠, 马, 兔 和 Pig. It has been validated for WB, IHC 和 ChIP.
产品编号 ABIN2781145
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GRHL3 抗体 (C-Term) (ABIN2781145)

抗原

See all GRHL3 抗体
GRHL3 (Grainyhead-Like 3 (GRHL3))

适用

人, 小鼠, 犬, 大鼠, Cow, 豚鼠, 马, 兔, Pig

宿主

  • 28
  • 2
兔

克隆类型

  • 28
  • 2
多克隆

标记

  • 21
  • 3
  • 2
  • 2
  • 1
  • 1
This GRHL3 antibody is un-conjugated

应用范围

  • 21
  • 16
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
  • 抗原表位

    • 10
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    GRHL3 Antibody - C-terminal region

    序列

    EEVFDALMLK TPDLKGLRNA ISEKYGFPEE NIYKVYKKCK RGILVNMDNN

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against GRHL3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human GRHL3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39489-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Darido, Georgy, Wilanowski, Dworkin, Auden, Zhao, Rank, Srivastava, Finlay, Papenfuss, Pandolfi, Pearson, Jane: "Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis." in: Cancer cell, Vol. 20, Issue 5, pp. 635-48, (2011) (PubMed).

  • 抗原

    GRHL3 (Grainyhead-Like 3 (GRHL3))

    别名

    GRHL3

    背景

    Background Information: GRHL3 is a member of the grainyhead family of transcription factors. GRHL3 interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.

    Gene Name: Grainyhead-like 3 (Drosophila)

    Alternative Symbols: SOM, VWS2, TFCP2L4

    Protein Name: Grainyhead-like protein 3 homolog

    分子量

    57 kDa, 70 kDa

    基因ID

    57822

    NCBI登录号

    NP_937817

    UniProt

    Q8TE85
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