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Glutaredoxin 2 抗体 (AA 1-124)

This anti-Glutaredoxin 2 antibody is a 兔 多克隆 antibody detecting Glutaredoxin 2 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7154050
发货至: 中国

Quick Overview for Glutaredoxin 2 抗体 (AA 1-124) (ABIN7154050)

抗原

See all Glutaredoxin 2 (GRX2) 抗体
Glutaredoxin 2 (GRX2)

适用

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宿主

  • 42
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克隆类型

  • 46
  • 2
多克隆

标记

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This Glutaredoxin 2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-124

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Glutaredoxin-2, mitochondrial protein (1-124AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Glutaredoxin 2 (GRX2)

    别名

    GLRX2

    背景

    Background: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

    Aliases: bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2) antibody, bA101E13.1 antibody, CGI133 antibody, Glrx2 antibody, GLRX2_HUMAN antibody, Glutaredoxin-2 antibody, Glutaredoxin-2, mitochondrial antibody, GRX2 antibody, mitochondrial antibody

    UniProt

    Q9NS18

    途径

    Cell RedoxHomeostasis
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