GABARAPL2 抗体 (AA 1-117)
Quick Overview for GABARAPL2 抗体 (AA 1-117) (ABIN7153521)
抗原
See all GABARAPL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-117
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交叉反应
- 人, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 2 protein (1-117AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))
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别名
- GABARAPL2
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背景
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Background: Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Aliases: ATG8 antibody, ATG8C antibody, FLC3A antibody, GABA(A) receptor-associated protein-like 2 antibody, Gabarapl2 antibody, Gamma-aminobutyric acid receptor-associated protein-like 2 antibody, Ganglioside expression factor 2 antibody, GATE-16 antibody, GATE16 antibody, GBRL2_HUMAN antibody, GEF-2 antibody, GEF2 antibody, General protein transport factor p16 antibody, Golgi-associated ATPase enhancer of 16 kDa antibody, MAP1 light chain 3-related protein antibody
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UniProt
- P60520
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途径
- Autophagy
抗原
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