FBP1 抗体 (AA 1-338)
Quick Overview for FBP1 抗体 (AA 1-338) (ABIN7153202)
抗原
See all FBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-338
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Fructose-1,6-bisphosphatase 1 protein (1-338AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))
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别名
- FBP1
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背景
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Background: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity, increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Aliases: 6-bisphosphatase 1 antibody, 6-bisphosphate 1-phosphohydrolase 1 antibody, D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody, D-fructose-1 antibody, EC 3.1.3.11 antibody, F16P1_HUMAN antibody, FBP antibody, FBP 1 antibody, FBP1 antibody, FBPase 1 antibody, Fructose 1 6 bisphosphatase 1 antibody, Fructose bisphosphatase 1 antibody, Fructose-1 antibody, Growth inhibiting protein 17 antibody, Liver fructose bisphosphatase antibody
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UniProt
- P09467
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途径
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport
抗原
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