FZD8 抗体 (AA 55-233)
Our Local Distributor
北京 101111
Quick Overview for FZD8 抗体 (AA 55-233) (ABIN7153193)
抗原
See all FZD8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 55-233
-
原理
- FZD8 Antibody
-
交叉反应
- 小鼠
-
纯化方法
- Protein G purified
-
纯度
- >95 %
-
免疫原
- Recombinant Human Frizzled-8 protein (55-233AA)
-
亚型
- IgG
-
-
anti-Frizzled Family Receptor 8 (FZD8) antibody
FZD8 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyVerified FZD8 适用: 人 WB, ELISA, IHC, IF, IEM 宿主: 山羊 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (AA 72-161) antibodyFZD8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠, Cow, 猴, 非洲爪蟾, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (Extracellular Domain) antibodyFZD8 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyFZD8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyFZD8 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- FZD8 (Frizzled Family Receptor 8 (FZD8))
-
别名
- FZD8
-
背景
-
Background: Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Coreceptor along with RYK of Wnt proteins, such as WNT1.
Aliases: Frizzled 8 seven transmembrane spanning receptor antibody, frizzled 8, seven transmembrane spanning receptor antibody, Frizzled family receptor 8 antibody, frizzled homolog 8 (Drosophila) antibody, Frizzled homolog 8 antibody, Frizzled-8 antibody, FZ 8 antibody, Fz-8 antibody, FZ8 antibody, FZD 8 antibody, FZD8 antibody, FZD8_HUMAN antibody, hFZ 8 antibody, hFz8 antibody, HGNC4046 antibody, Homolog of Drosophila Frizzled 8 antibody
-
UniProt
- Q9H461
-
途径
- WNT signaling
抗原
-
