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FFAR1 抗体 (AA 143-178)

This anti-FFAR1 antibody is a 兔 多克隆 antibody detecting FFAR1 in ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7153159
发货至: 中国

Quick Overview for FFAR1 抗体 (AA 143-178) (ABIN7153159)

抗原

See all FFAR1 抗体
FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FFAR1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 143-178

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Free fatty acid receptor 1 protein (143-178AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

    别名

    FFAR1

    背景

    Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

    Aliases: FFA1R antibody, FFAR 1 antibody, Ffar1 antibody, FFAR1_HUMAN antibody, Free fatty acid receptor 1 antibody, G protein coupled receptor 40 antibody, G-protein coupled receptor 40 antibody, GPCR40 antibody, GPR 40 antibody, GPR40 antibody

    UniProt

    O14842

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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