FFAR1 抗体 (AA 143-178)
Quick Overview for FFAR1 抗体 (AA 143-178) (ABIN7153159)
抗原
See all FFAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 143-178
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Free fatty acid receptor 1 protein (143-178AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
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别名
- FFAR1
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背景
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Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.
Aliases: FFA1R antibody, FFAR 1 antibody, Ffar1 antibody, FFAR1_HUMAN antibody, Free fatty acid receptor 1 antibody, G protein coupled receptor 40 antibody, G-protein coupled receptor 40 antibody, GPCR40 antibody, GPR 40 antibody, GPR40 antibody
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UniProt
- O14842
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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