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FFAR1 抗体 (Internal Region)

FFAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261716
发货至: 中国
  • 抗原 See all FFAR1 抗体
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    抗原表位
    • 15
    • 10
    • 8
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 60
    • 31
    • 15
    • 5
    • 5
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 59
    • 2
    • 1
    克隆类型
    • 60
    • 2
    多克隆
    标记
    • 22
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FFAR1 antibody is un-conjugated
    应用范围
    • 47
    • 20
    • 13
    • 13
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    GPR40 Antibody detects endogenous levels of total GPR40.
    预测反应
    Pig,Bovine,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human GPR40, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product FFAR1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    别名
    FFAR1 (FFAR1 产品)
    别名
    FFAR1 antibody, GPR40 antibody, FFA1R antibody, GPCR40 antibody, Gpr40 antibody, free fatty acid receptor 1 antibody, FFAR1 antibody, Ffar1 antibody
    背景

    Description: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

    Gene: FFAR1

    分子量
    31 kDa
    基因ID
    2864
    UniProt
    O14842
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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