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FOXN1 抗体 (AA 1-160) (Biotin)

This anti-FOXN1 antibody is a 兔 多克隆 antibody detecting FOXN1 in ELISA. Suitable for 人.
产品编号 ABIN7153071
发货至: 中国

Quick Overview for FOXN1 抗体 (AA 1-160) (Biotin) (ABIN7153071)

抗原

See all FOXN1 抗体
FOXN1 (Forkhead Box N1 (FOXN1))

适用

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宿主

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克隆类型

  • 45
多克隆

标记

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This FOXN1 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 1-160

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Forkhead box protein N1 protein (1-160AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FOXN1 (Forkhead Box N1 (FOXN1))

    别名

    FOXN1

    背景

    Background: Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master regulator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps through which TECs mature to acquire their full functionality. Regulates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, including MHC Class II, DLL4, CCL25, CTSL, CD40 and PAX1. Regulates the differentiation of the immature TECs into functional cortical TECs (cTECs) and medullary TECs (mTECs). Essential for maintenance of mTECs population in the postnatal thymus. Involved in the morphogenesis and maintenance of the three-dimensional thymic microstructure which is necessary for a fully functional thymus. Plays an important role in the maintenance of hematopoiesis and particularly T lineage progenitors within the bone marrow niche with age. Essential for the vascularization of the thymus anlage. Promotes the terminal differentiation of epithelial cells in the epidermis and hair follicles, partly by negatively regulating the activity of protein kinase C (By similarity). Plays a crucial role in the early prenatal stages of T-cell ontogeny (PubMed:21507891).

    Aliases: FKHL20 antibody, Forkhead box N1 antibody, Forkhead box protein N1 antibody, FOXN 1 antibody, FOXN1 antibody, FOXN1_HUMAN antibody, RONU antibody, Rowett nude antibody, Transcription factor winged-helix nude antibody, WHN antibody, Winged helix nude antibody, Winged-helix transcription factor nude antibody

    UniProt

    O15353
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