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FERMT2 抗体 (AA 155-232) (Biotin)

This anti-FERMT2 antibody is a 兔 多克隆 antibody detecting FERMT2 in ELISA. Suitable for 人.
产品编号 ABIN7152703
发货至: 中国

Quick Overview for FERMT2 抗体 (AA 155-232) (Biotin) (ABIN7152703)

抗原

See all FERMT2 抗体
FERMT2 (Fermitin Family Member 2 (FERMT2))

适用

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宿主

  • 37
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克隆类型

  • 37
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多克隆

标记

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This FERMT2 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 155-232

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Fermitin family homolog 2 protein (155-232AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FERMT2 (Fermitin Family Member 2 (FERMT2))

    别名

    FERMT2

    背景

    Background: Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.

    Aliases: FLJ34213 antibody, FLJ44462 antibody, UNC112 antibody, FERM2_HUMAN antibody, Fermitin family homolog 2 antibody, Fermt2 antibody, KIND2 antibody, Kindlin-2 antibody, MIG-2 antibody, MIG2 antibody, Mitogen-inducible gene 2 protein antibody, PH domain-containing family C member 1 antibody, Pleckstrin homology domain containing family C (with FERM domain) member 1 antibody, Pleckstrin homology domain-containing family C member 1 antibody, PLEKHC1 antibody, UNC112B antibody

    UniProt

    Q96AC1

    途径

    Cell-Cell Junction Organization
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