FBXW11 抗体 (AA 1-140)
Quick Overview for FBXW11 抗体 (AA 1-140) (ABIN7152490)
抗原
See all FBXW11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-140
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human F-box/WD repeat-containing protein 11 protein (1-140AA)
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亚型
- IgG
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anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 1-529) antibody
FBXW11 适用: 人 ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 1-140) antibodyFBXW11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 168-196) antibodyFBXW11 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18056 unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 175-204), (Middle Region) antibodyFBXW11 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (N-Term) antibodyFBXW11 适用: 人, 小鼠, 犬, 豚鼠, 兔, 小鸡, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 38-87) antibodyFBXW11 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (N-Term) antibodyFBXW11 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
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别名
- FBXW11
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背景
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Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. Involved in the oxidative stress-induced a ubiquitin-mediated decrease in RCAN1. Mediates the degradation of CDC25A induced by ionizing radiation in cells progressing through S phase and thus may function in the intra-S-phase checkpoint. Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and phosphorylated PER2. Is target of human immunodeficiency virus type 1 (HIV-1) protein VPU to polyubiquitinate and deplete BST2 from cells and antagonize its antiviral action.
Aliases: beta Transducin Repeat Containing Protein 2 antibody, BTRC2 antibody, BTRCP2 antibody, F-box and WD repeats protein beta-TrCP2 antibody, F-box and WD-40 Domain Protein 1B antibody, F-box Protein FBW1B antibody, F-box/WD repeat-containing protein 11 antibody, F-box/WD repeat-containing protein 1B antibody, FBW1B antibody, FBW1B_HUMAN antibody, FBXW11 antibody, FBXW1B antibody, Homologous to Slimb protein antibody, HOS antibody
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UniProt
- Q9UKB1
抗原
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