FBXW11 抗体
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- 抗原 See all FBXW11 抗体
- FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXW11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- F-box and WD repeat domain containing 11
- 亚型
- IgG
- Top Product
- Discover our top product FBXW11 Primary Antibody
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anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 1-140) antibody
FBXW11 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) antibodyFBXW11 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 1-529) antibodyFBXW11 适用: 人 ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 1-140) antibodyFBXW11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 168-196) antibodyFBXW11 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18056 unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 175-204), (Middle Region) antibodyFBXW11 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 38-87) antibodyFBXW11 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (N-Term) antibodyFBXW11 适用: 人, 小鼠, 犬, 豚鼠, 兔, 小鸡, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (N-Term) antibodyFBXW11 适用: 人, 小鼠, 犬, Cow, 小鸡, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (N-Term) antibodyFBXW11 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
- 别名
- FBXW11 (FBXW11 产品)
- 别名
- BTRC2 antibody, BTRCP2 antibody, FBW1B antibody, FBXW1B antibody, Fbw11 antibody, Hos antibody, 2310065A07Rik antibody, AA536858 antibody, Fbxw1b antibody, HOS antibody, btrc2 antibody, fbxw11a antibody, wu:fa12e12 antibody, wu:fb11f03 antibody, zgc:63728 antibody, fbxw11 antibody, fbxw11b antibody, fbxw1b antibody, wu:fd14d12 antibody, wu:fi43f07 antibody, F-box and WD repeat domain containing 11 antibody, F-box and WD-40 domain protein 11 antibody, F-box/WD repeat-containing protein 11 antibody, F-box and WD repeat domain containing 11b antibody, F-box and WD repeat domain containing 11a antibody, FBXW11 antibody, Fbxw11 antibody, LOC100199403 antibody, fbxw11b antibody, fbxw11a antibody
- 背景
- Synonyms:BTRCP2, FBW1B, FBXW1B, KIAA0696 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. SCF(FBXW11) mediates the ubiquitination of CEP68, this is required for centriole separation during mitosis(PubMed:25503564). Involved in the oxidative stress-induced a ubiquitin-mediated decrease in RCAN1. Mediates the degradation of CDC25A induced by ionizing radiation in cells progressing through S phase and thus may function in the intra-S-phase checkpoint. Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and phosphorylated PER2. Is target of human immunodeficiency virus type 1(HIV-1) protein VPU to polyubiquitinate and deplete BST2 from cells and antagonize its antiviral action.
- 分子量
- 61 kDa
- 基因ID
- 23291
- UniProt
- Q9UKB1
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