Exportin 2 抗体 (AA 713-971) (HRP)
Quick Overview for Exportin 2 抗体 (AA 713-971) (HRP) (ABIN7152324)
抗原
See all Exportin 2 (CSE1L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 713-971
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Exportin-2 protein (713-971AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
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别名
- CSE1L
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背景
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Background: Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Aliases: CAS antibody, Cellular apoptosis susceptibility protein antibody, Chromosome segregation 1 (yeast homolog) like antibody, Chromosome segregation 1 Like antibody, Chromosome segregation 1 like protein antibody, Chromosome segregation 1-like protein antibody, Chromosome segregation gene CSE1 antibody, CSE 1 antibody, CSE 1 chromosome segregation 1 like antibody, CSE 1 chromosome segregation 1 like protein antibody, CSE 1L antibody, CSE1 antibody, CSE1 chromosome segregation 1 like (yeast) antibody, CSE1 chromosome segregation 1 like antibody, CSE1 chromosome segregation 1 like protein antibody, CSE1L antibody, Exp 2 antibody, Exp2 antibody, Exportin 2 antibody, Exportin-2 antibody, Exportin2 antibody, Importin alpha re exporter antibody, Importin-alpha re-exporter antibody, MGC117283 antibody, MGC130036 antibody, MGC130037 antibody, XPO 2 antibody, XPO2 antibody, XPO2_HUMAN antibody
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UniProt
- P55060
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途径
- Protein targeting to Nucleus
抗原
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