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EPH Receptor B3 抗体 (AA 261-390) (HRP)

This anti-EPH Receptor B3 antibody is a 兔 多克隆 antibody detecting EPH Receptor B3 in ELISA. Suitable for 人.
产品编号 ABIN7151867
发货至: 中国

Quick Overview for EPH Receptor B3 抗体 (AA 261-390) (HRP) (ABIN7151867)

抗原

See all EPH Receptor B3 (EPHB3) 抗体
EPH Receptor B3 (EPHB3)

适用

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宿主

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克隆类型

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多克隆

标记

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This EPH Receptor B3 antibody is conjugated to HRP

应用范围

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ELISA
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    AA 261-390

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Ephrin type-B receptor 3 protein (261-390AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    EPH Receptor B3 (EPHB3)

    别名

    EPHB3

    背景

    Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca. Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt.

    Aliases: Cek10 antibody, EK2 antibody, Embryonic kinase 2 antibody, EPH Like Tyrosine Kinase 2 antibody, EPH receptor B3 antibody, EPH-like kinase 2 antibody, ephb3 antibody, EPHB3_HUMAN antibody, Ephrin receptor EphB3 antibody, Ephrin type B receptor 3 antibody, Ephrin type-B receptor 3 antibody, ETK2 antibody, hEK2 antibody, Human Embryo Kinase 2 antibody, Mdk5 antibody, Sek4 antibody, TYRO6 antibody, Tyrosine protein kinase receptor HEK2 antibody, Tyrosine protein kinase TYRO6 antibody, Tyrosine-protein kinase TYRO6 antibody

    UniProt

    P54753

    途径

    RTK signaling
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