SH3GLB1 抗体 (AA 1-365)
Quick Overview for SH3GLB1 抗体 (AA 1-365) (ABIN7151644)
抗原
See all SH3GLB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-365
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Endophilin-B1 protein (1-365AA)
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亚型
- IgG
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anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (C-Term) antibody
Verified SH3GLB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 1-365) antibodySH3GLB1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B3-A5 unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 1-365) antibodySH3GLB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 1-366) antibodySH3GLB1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B3-A5 unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 120-365) antibodySH3GLB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 59-86) antibodySH3GLB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15350 unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 58-107) antibodySH3GLB1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (N-Term) antibodySH3GLB1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (Tyr80) antibodySH3GLB1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (C-Term) antibodySH3GLB1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
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别名
- SH3GLB1
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背景
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Background: May be required for normal outer mitochondrial membrane dynamics (PubMed:15452144). Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (PubMed:11604418). Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588). Isoform 1 acts proapoptotic in fibroblasts. Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2) (PubMed:17891140). Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation (PubMed:21068542). Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). Isoform 2 acts antiapoptotic in neuronal cells, involved in maintenance of mitochondrial morphology and promotes neuronal viability.
Aliases: Bax interacting factor 1 antibody, Bax-interacting factor 1 antibody, Bif 1 antibody, Bif antibody, Bif-1 antibody, CGI 61 antibody, dJ612B15.2 antibody, Endophilin B1 antibody, Endophilin-B1 antibody, PPP1R70 antibody, Protein phosphatase 1 regulatory subunit 70 antibody, SH3 containing protein SH3GLB1 antibody, SH3 domain GRB2 like endophilin B1 antibody, SH3 domain-containing GRB2-like protein B1 antibody, Sh3glb1 antibody, SH3p13 antibody, SHLB1_HUMAN antibody
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UniProt
- Q9Y371
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途径
- Autophagy
抗原
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