RNF43 抗体 (AA 566-697) (Biotin)
Quick Overview for RNF43 抗体 (AA 566-697) (Biotin) (ABIN7151199)
抗原
See all RNF43 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 566-697
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human E3 ubiquitin-protein ligase RNF43 protein (566-697AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RNF43 (Ring Finger Protein 43 (RNF43))
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别名
- RNF43
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背景
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Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
Aliases: RNF43 antibody, E3 ubiquitin-protein ligase RNF43 antibody, EC 2.3.2.27 antibody, RING finger protein 43 antibody, RING-type E3 ubiquitin transferase RNF43 antibody
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UniProt
- Q68DV7
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途径
- WNT signaling
抗原
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