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RNF139 抗体 (AA 510-664)

This 兔 多克隆 anti-RNF139 antibody specifically detects RNF139 in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7151154
发货至: 中国
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Quick Overview for RNF139 抗体 (AA 510-664) (ABIN7151154)

抗原

See all RNF139 抗体
RNF139 (Ring Finger Protein 139 (RNF139))

适用

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宿主

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克隆类型

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多克隆

标记

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This RNF139 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 510-664

    原理

    RNF139 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human E3 ubiquitin-protein ligase RNF139 protein (510-664AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RNF139 (Ring Finger Protein 139 (RNF139))

    别名

    RNF139

    背景

    Background: E3-ubiquitin ligase, acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.

    Aliases: RNF139 antibody, TRC8 antibody, E3 ubiquitin-protein ligase RNF139 antibody, EC 2.3.2.27 antibody, RING finger protein 139 antibody, RING-type E3 ubiquitin transferase RNF139 antibody, Translocation in renal carcinoma on chromosome 8 protein antibody

    UniProt

    Q8WU17
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