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- 抗原 See all RNF2 抗体
- RNF2 (Ring Finger Protein 2 (RNF2))
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抗原表位
- AA 158-290
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase RING2 protein (158-290AA)
- 亚型
- IgG
- Top Product
- Discover our top product RNF2 Primary Antibody
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anti-Ring Finger Protein 2 (RNF2) (AA 192-290) antibody
RNF2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6C2 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 192-290) antibodyRNF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 1-336) antibodyRNF2 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 164-223) antibodyRNF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C1 unconjugated
anti-Ring Finger Protein 2 (RNF2) antibodyRNF2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) antibodyRNF2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 2H12 unconjugated Recombinant Antibody
anti-Ring Finger Protein 2 (RNF2) (Middle Region) antibodyRNF2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 198-232) antibodyRNF2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB52337 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 1-100) antibodyRNF2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 165-199) antibodyRNF2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB52402 unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RNF2 (Ring Finger Protein 2 (RNF2))
- 别名
- RNF2 (RNF2 产品)
- 别名
- BAP-1 antibody, BAP1 antibody, DING antibody, HIPI3 antibody, RING1B antibody, RING2 antibody, AI326319 antibody, AI450156 antibody, AU019207 antibody, Ring1B antibody, dinG antibody, fa19h05 antibody, ring1b antibody, wu:fa19h05 antibody, wz4556 antibody, bap-1 antibody, bap1 antibody, ding antibody, hipi3 antibody, ring2 antibody, ring finger protein 2 antibody, ring finger protein 2 L homeolog antibody, RNF2 antibody, Rnf2 antibody, rnf2 antibody, rnf2.L antibody
- 背景
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Background: E3 ubiquitin-protein ligase that mediates monoubiquitination of \\\'Lys-119\\\' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. E3 ubiquitin-protein ligase activity is enhanced by BMI1/PCGF4. Acts as the main E3 ubiquitin ligase on histone H2A of the PRC1 complex, while RING1 may rather act as a modulator of RNF2/RING2 activity. In resting B- and T-lymphocytes, interaction with AURKB leads to block its activity, thereby maintaining transcription in resting lymphocytes.
Aliases: BAP 1 antibody, BAP1 antibody, DING antibody, DinG protein antibody, E3 ubiquitin protein ligase RING 2 antibody, E3 ubiquitin protein ligase RING2 antibody, E3 ubiquitin-protein ligase RING2 antibody, HIP2 interacting protein 3 antibody, HIP2-interacting protein 3 antibody, HIPI 3 antibody, HIPI3 antibody, Huntingtin interacting protein 2 interacting protein 3 antibody, Huntingtin-interacting protein 2-interacting protein 3 antibody, OTTHUMP00000060668 antibody, Polycomb M33 interacting protein Ring 1B antibody, Polycomb M33 interacting protein Ring1B antibody, Protein DinG antibody, RING 1B antibody, RING 2 antibody, RING finger protein 1B antibody, RING finger protein 2 antibody, RING finger protein BAP 1 antibody, RING finger protein BAP-1 antibody, RING finger protein BAP1 antibody, RING1b antibody, RING2_HUMAN antibody, RNF 2 antibody, Rnf2 antibody
- UniProt
- Q99496
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