STUB1 抗体 (AA 1-48)
Quick Overview for STUB1 抗体 (AA 1-48) (ABIN7151009)
抗原
See all STUB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-48
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human E3 ubiquitin-protein ligase CHIP protein (1-48AA)
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亚型
- IgG
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anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibody
STUB1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) antibodySTUB1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, Pig, 马, 猴, 小鸡, Hamster, Avian, Cat, 驴, 山羊, 兔, 绵羊 WB 宿主: 山羊 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (C-Term) antibodyVerified STUB1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231) antibodySTUB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibodySTUB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 51-303) antibodySTUB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231), (C-Term) antibodySTUB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7393 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (N-Term) antibodySTUB1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (C-Term) antibodySTUB1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 204-303) antibodySTUB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E12 unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
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别名
- STUB1
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背景
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Background: E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. Mediates polyubiquitination of DNA polymerase beta (POLB) at \\\'Lys-41\\\', \\\'Lys-61\\\' and \\\'Lys-81\\\', thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF-BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. Ubiquitinates EPHA2 and may regulate the receptor stability and activity through proteasomal degradation. Negatively regulates the suppressive function of regulatory T-cells (Treg) during inflammation by mediating the ubiquitination and degradation of FOXP3 in a HSPA1A/B-dependent manner (PubMed:23973223).
Aliases: Antigen NY CO 7 antibody, Antigen NY-CO-7 antibody, C terminus of Hsp70-interacting protein antibody, Carboxy terminus of Hsp70 interacting protein antibody, Carboxy terminus of Hsp70-interacting protein antibody, Carboxy terminus of Hsp70p interacting protein antibody, CHIP antibody, CHIP_HUMAN antibody, CLL associated antigen KW 8 antibody, CLL-associated antigen KW-8 antibody, E3 ubiquitin protein ligase CHIP antibody, E3 ubiquitin-protein ligase CHIP antibody, Heat shock protein A binding protein 2 (c terminal) antibody, HSPABP2 antibody, NY CO 7 antibody, PP1131 antibody, SDCCAG7 antibody, Serologically defined colon cancer antigen 7 antibody, STIP1 homology and U Box containing protein 1 antibody, STIP1 homology and U box containing protein 1 E3 ubiquitin protein ligase antibody, STIP1 homology and U box-containing protein 1 antibody, STUB 1 antibody, STUB1 antibody, UBOX 1 antibody, UBOX1 antibody
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UniProt
- Q9UNE7
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途径
- Regulation of Hormone Metabolic Process, Response to Water Deprivation
抗原
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