POLR3E 抗体 (AA 1-260)
Quick Overview for POLR3E 抗体 (AA 1-260) (ABIN7150462)
抗原
See all POLR3E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-260
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human DNA-directed RNA polymerase III subunit RPC5 protein (1-260AA)
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亚型
- IgG
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anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (Internal Region) antibody
POLR3E 适用: 人 ELISA, IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (Internal Region) antibodyPOLR3E 适用: 人, 小鼠 ELISA, IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (AA 1-666) antibodyPOLR3E 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4F4 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (AA 89-323) antibodyPOLR3E 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) antibodyPOLR3E 适用: 人, 猴 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (N-Term) antibodyPOLR3E 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (AA 191-240) antibodyPOLR3E 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
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别名
- POLR3E
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背景
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Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Aliases: POLR3E antibody, KIAA1452 antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, RNA polymerase III subunit C5 antibody, DNA-directed RNA polymerase III 80 kDa polypeptide antibody
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UniProt
- Q9NVU0
抗原
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