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- 抗原 See all POLR3E 抗体
- POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR3E antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- POLR3E Antibody detects endogenous levels of total POLR3E.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human POLR3E, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product POLR3E Primary Antibody
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anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (Internal Region) antibody
POLR3E 适用: 人 ELISA, IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (AA 1-260) antibodyPOLR3E 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (Internal Region) antibodyPOLR3E 适用: 人, 小鼠 ELISA, IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (AA 1-666) antibodyPOLR3E 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4F4 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (AA 89-323) antibodyPOLR3E 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) antibodyPOLR3E 适用: 人, 猴 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E) (AA 191-240) antibodyPOLR3E 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
- 别名
- POLR3E (POLR3E 产品)
- 别名
- RPC5 antibody, SIN antibody, Sin antibody, MGC78924 antibody, RGD1308086 antibody, wu:fb12d10 antibody, wu:fs42e03 antibody, zgc:55592 antibody, RNA polymerase III subunit E antibody, polymerase (RNA) III (DNA directed) polypeptide E antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, POLR3E antibody, Polr3e antibody, polr3e.L antibody, polr3e antibody, LOC608689 antibody
- 背景
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Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Gene: POLR3E
- 分子量
- 80kDa
- 基因ID
- 55718
- UniProt
- Q9NVU0
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