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NDEL1 抗体 (pSer242)

This anti-NDEL1 antibody (ABIN710816) is a Rabbit Polyclonal antibody detecting NDEL1 in WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro). Suitable for Human, Mouse.
产品编号 ABIN710816
发货至: 中国

Quick Overview for NDEL1 抗体 (pSer242) (ABIN710816)

抗原

See all NDEL1 抗体
NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

适用

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人, 小鼠

宿主

  • 88
  • 5
  • 1

克隆类型

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多克隆

标记

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This NDEL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pSer242

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human NDEL1 around the phosphorylation site of Ser242

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

    别名

    NDEL1

    背景

    Synonyms: EOPA, NDE2, NUDEL, MITAP1, NDE1L1, Nuclear distribution protein nudE-like 1, Protein Nudel, Mitosin-associated protein 1, NDEL1

    Background: Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.

    基因ID

    81565

    UniProt

    Q9GZM8

    途径

    Regulation of Cell Size
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