IKZF1 抗体 (AA 1-265) (FITC)
Quick Overview for IKZF1 抗体 (AA 1-265) (FITC) (ABIN7150364)
抗原
See all IKZF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-265
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human DNA-binding protein Ikaros protein (1-265AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
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别名
- IKZF1
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背景
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Background: Transcription regulator of hematopoietic cell differentiation (PubMed:17934067). Binds gamma-satellite DNA (PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed:17135265, PubMed:17934067).
Aliases: CLL associated antigen KW 6 antibody, DNA-binding protein Ikaros antibody, hIk 1 antibody, Hs.54452 antibody, IK1 antibody, Ikaros (zinc finger protein) antibody, IKAROS antibody, IKAROS family zinc finger 1 (Ikaros) antibody, Ikaros family zinc finger protein 1 antibody, Ikzf1 antibody, IKZF1_HUMAN antibody, LYF1 antibody, Lymphoid transcription factor LyF-1 antibody, PRO0758 antibody, Zinc finger protein subfamily 1A 1 (Ikaros) antibody, Zinc finger protein subfamily 1A 1 antibody, Zinc finger protein, subfamily 1A, member 1 antibody, ZNFN1A1 antibody
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UniProt
- Q13422
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途径
- Production of Molecular Mediator of Immune Response
抗原
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